Learn about SARMs…
In today’s piece we delve into the world of Selective Androgen Receptor Modulators – more commonly known as SARMs – and how they can be used as an alternative to anabolic steroids to build muscle mass, decrease fat levels and increase strength (amongst other things).
For more information on SARMs please visit: http://101sarms.com/
Although not technically a SARM, Cardarine (GW-501516) is often lumped with other SARMs due to the fact that it has similar effects. Instead of interacting with the androgen receptor, it interacts with the Peroxisome proliferator-actives receptor (a receptor which is involved in lipid metabolism) and 5’ AMP-activated protein kinase (an enzyme that plays an important role in energy homeostasis within cells).
Initial research on Cardarine showed that it may be able to alter abnormalities in pre-diabetic people, and with more than 30% of the adult population and over 15% of the child population in the USA considered clinically obese, Cardarine can be considered as a potential treatment. More trials on this SARM carried out on monkeys and rats showed a plethora of positive benefits, including increased muscle mass, decreased fat mass, elimination of diet-induced type II diabetes, increase in HDL and decrease in LDL.
Although it does have plenty of positive aspects, it was discovered in several studies that high dosages for long periods may cause cancer. This is contradictory to what was found in other studies – studies that marked Cardarine as completely harmless due to the fact that it doesn’t negatively impact the HPTA, nor does it induce the side effects commonly seen when taking other SARMs and/or anabolic steroids.
If you’re reading this then it’s highly likely that you’re a gym goer, athlete or bodybuilder and are interested in finding out how this SARM can assist you in building muscle, burning fat and improving your performance? Although it can build muscle, it is typically used for cutting and recomposition cycles, in addition to improving athletic performance. Due to the mechanisms along which is works it is extremely effective at increase both aerobic and anaerobic endurance. This is can be of huge benefit to bodybuilders as well as athletes as it will help those lifting weights to recover more quickly between sets, in addition to being able to increase the overall volume of workouts.
Dosing for Cardarine should be between 10-20mg per day for no longer than 8 weeks.
Liagndrol, also known as LGD-4033, is a non-steroidal SARM that is orally bioavailable. It has completed Phase I clinical trials during which it was ascertained that humans can tolerate 22mg per day for two weeks and that LGD-4033 increased lean muscle mass, decreased fat mass, increased strength and improved well-being. In addition to this, it also decreased bone turnover rate and is therefore a potential treatment for those suffering from osteoporosis.
In terms of side effects, Lignadrol does not appear to lower gonadotropins (LH and FSH) or increase either PSA or estrogen levels, however it is capable of decreasing total and free testosterone levels, therefore a full post cycle therapy using SERMs is highly required. At doses of 5mg or less per day will decrease testosterone levels yet it will stay within the normal range, however doses above 5mg will decrease testosterone to below normal levels and may also decrease HDL levels significantly.
Before using any SARM it is important that you carry out full research on the compound(s) you intend to use. Although they typically have fewer side effects than anabolic steroids, they should not be taken lightly and still do have some negative effects.
For further information please visit the website linked at the top of the page.